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Elongation factor‐2 kinase regulates TG2/β1 integrin/Src/uPAR pathway and epithelial–mesenchymal transition mediating pancreatic cancer cells invasion |
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| Authors: | Ahmed A Ashour Nilgun Gurbuz Sultan Neslihan Alpay Abdel‐Aziz H Abdel‐Aziz Ahmed M Mansour Longfei Huo Bulent Ozpolat |
| Institution: | 1. Department of Experimental Therapeutics, The University of Texas, M.D. Anderson Cancer Center, , Houston, TX, USA;2. Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al‐Azhar University, , Cairo, Egypt;3. Department of Molecular & Cellular Oncology, The University of Texas, M.D. Anderson Cancer Center, , Houston, TX, USA;4. Non‐Coding RNA, The University of Texas, M.D. Anderson Cancer Center, , Houston, TX, USA |
| Abstract: | |
| Keywords: | eEF‐2K Ca2+/calmodulin‐dependent kinase III tissue transglutaminase rottlerin Src integrin uPAR MMP‐2 EMT pancreatic ductal adenocarcinoma |