Fatty acid acylation of proteins in Physarum polycephalum |
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Authors: | M Monteiro A I Magee |
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Affiliation: | National Institute for Medical Research, Mill Hill, London, U.K. |
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Abstract: | We have investigated the occurrence of protein-fatty acid acylation by metabolic incorporation of [3H]myristic and [3H]palmitic acids in Physarum polycephalum. We show that this organism contains fatty acylated proteins with mainly myristic acid covalently attached in alkali-stable linkages, probably amides. We find no evidence for ester-linked fatty acids, in contrast to the situation in vertebrate cells. |
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