Save the tree of life or get lost in the woods |
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Authors: | Ruben E Valas Philip E Bourne |
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Affiliation: | (1) Bioinformatics Program, University of California, 9500 Gilman Drive, 92093 San Diego, La Jolla, CA, USA;(2) Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, 9500 Gilman Drive, 92093 San Diego, La Jolla, CA, USA |
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Abstract: | Background The wealth of prokaryotic genomic data available has revealed that the histories of many genes are inconsistent, leading some to question the value of the tree of life hypothesis. It has been argued that a tree-like representation requires suppressing too much information, and that a more pluralistic approach is necessary for understanding prokaryotic evolution. We argue that trees may still be a useful representation for evolutionary histories in light of new data. |
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