Dehydroepiandrosterone sulfate effect at aldosterone level under cold exposure

It had been shown that the blockade with dehydroepiandrosterone sulfate (DHEAS) affects enhanced aldosterone level in doses 1, 5 and 30 mg/kg without the dose dependence under multi-repeated cold exposure. These DHEAS effects are realized through micro-opioid receptors. The DHEAS (30 mg/kg) blocking effect was manifested too, but not through micro-opioid receptors under acute cold exposure.