Preparation and receptor binding affinities of cyclic C-terminal neurotensin (8-13) and (9-13) analogues. |
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| Authors: | J T Lundquist T A Dix |
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| Affiliation: | Department of Pharmaceutical Sciences, Medical University of South Carolina, Charleston 29425, USA. |
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| Abstract: | Cyclic analogues of neurotensin (NT) C-terminal fragments NT(8-13) and NT(9-13) were produced via intramolecular nucleophilic substitution of the Tyr(11) phenoxide anion on a 6-bromohexanoyl side chain substituted at position 8 or 9 and tested for NT receptor binding affinity. |
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