首页 | 本学科首页   官方微博 | 高级检索  
   检索      


Local bacillus Calmette-Guérin therapy for bovine vulval papilloma and carcinoma
Authors:F W G Hill  V P M G Rutten  M H Hoyer  W R Klein  J W Koten  P A Steerenberg  E J Ruitenberg  W Den Otter
Institution:(1) Faculty of Veterinary Science, University of Zimbabwe, Mount Pleasant, P.O. Box MP 167, Harare, Zimbabwe;(2) Department of Immunology, Faculty of Veterinary Medicine, Institute of Infectious Diseases and Immunology, Yalelaan 1, 3584 CL Utrecht, The Netherlands;(3) Department of General and Large Animal Surgery, Faculty of Veterinary Medicine, P.O. Box 80.165, 3508 TD Utrecht, The Netherlands;(4) Department of Pathology, University Hospital Utrecht, P.O. Box. 85.500, 3508 GA Utrecht, The Netherlands;(5) National Institute of Public Health and Environmental Protection, P.O. Box 1, 3720 BA Bilthoven, The Netherlands;(6) Red Cross Blood Transfusion Service, Central Laboratory of the Netherlands, Plesmanlaan 125, 1066 CX Amsterdam, The Netherlands
Abstract:Thirty cows from a pedigree Friesian dairy herd with bovine vulva papilloma and carcinoma were treated by intralesional injections of live bacillus Calmette-Guérin (BCG). This treatment induced total regression of all of six carcinomas. Whilst, after treatment, limited regression was also observed in advanced papillomas, BCG has little or no effect on the early stages of papillomas. This is the first study of BCG therapy in this type of cancer.
Keywords:Immunotherapy  BCG  Bovine vulval papilloma-carcinoma
本文献已被 SpringerLink 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号