1. Laboratoire d''Enzymologie Physico-chimique et Moléculaire Faculté des Sciences, 91400 Orsay, France;2. Laboratoire d''Enzymologie du Centre National de la Recherche Scientifique 91190 Gif-sur-Yvette, France;3. Centre de Génétique Moléculaire du Centre National de la Recherche Scientifique 91190 Gif-sur-Yvette, France
Abstract:
We have undertaken a study of the mechanism of bovine liver glutamate dehydrogenase self-association with scattered light temperature-jump and stopped-flow relaxation techniques. Our results indicate a “random association” mechanism in which association-dissociation reactions occur between all polymerized forms of the oligomer according to