Serumprotein polymorphisms in Iran |
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Authors: | Mansur Bajatzadeh Hubert Walter |
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Institution: | 1. Sektion Humangenetik, Anthropologisches Institut der Universit?t Mainz, Mainz, Germany
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Abstract: | Summary The results of a population genetic investigation on Iranians are given and compared to the results obtained on other populations
from Southwestern and Southern Asia. Our total material from Iran comprises n=1020 nonrelated male and female individuals
of different age. The following serum groups have been typed: Hp, Gc, Gm, and Inv. In general there exist no remarkable age
or sex differences in the distribution of phenotypes and alleles (the only exception: sex differences in the distribution
of the Gm (7)-phenotype). The regional distribution of phenotypes and alleles yield no marked differences, too, apart from
the Invphenotypes, however. For the total material of Iran the following alleles frequencies could be calculated: Hp1=0.3045, Hp2=0.6595, Gc2=0.3405; Gm1=0.1780, Gm1,2=0.0537, Gm1,5=0.0632, Gm5=0.7051. The Gm (7)-phenotype turned out to be 36.6%; the Inv (1)-phenotype amounts to 25.6%. Comparing with other populations,
especially Pakistani and Indian samples, some heterogeneity in the distribution of phenotypes and alleles within Southwestern
and Southern Asia was to be demonstrated. Some distributional trends of alleles frequencies shall be mentioned here: the increase
of Hp2, Gc1, and Gm1 alleles from West towards East, and in the opposite direction the decrease of Hp1, Gc2, and Gm5 alleles. Selective acting forces are supposed to be most important factors for this.
D77 |
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