Amino acid sequence of Kalinowaski's Tinamou (Nothoprocta kalinowskii) hemoglobin and the rate of evolution of bird alphaD-globin |
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Authors: | Eguchi Y Eguchi T |
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Institution: | (1) Research Laboratory Center, Faculty of Medicine, University of the Ryukyus, 207 Uehara, Nishihara-Cho, Okinawa, 903-0125, Japan;(2) Department of Biochemistry, Faculty of Medicine, University of the Ryukyus, 207 Uehara, Nishihara-Cho, Okinawa, 903-0125, Japan |
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Abstract: | Two hemoglobin components are recognized in erythrocytes of the adult Tinamou. We determined the amino acid sequences of Tinamou D-, A-, and -globins from intact globin chains and several chemically cleaved fragments. A remarkable feature of Tinamou hemoglobin was a deletion in the D-globin chain. This has not been reported in the literature, except in pigeon embryonic D-globin. The amino acid sequences of Tinamou globin were highly similar to those of Ostrich and Rhea hemoglobin. Comparison between Tinamou, Ostrich, and Rhea that suggested the evolution speed of globin, D = A > , was related with the early appearance birds. The important residues in Tinamou hemoglobin as the heme contact and oxygen binding regions were highly conserved in other species. |
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Keywords: | Amino acid sequence rate of evolution hemoglobin Tinamou |
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