Mescaline-induced changes of brain-cortex ribosomes. Effect of mescaline on the hydrogen-bonded structure of ribonucleic acid of brain-cortex ribosomes |
| |
| Authors: | R. K. Datta and J. J. Ghosh |
| |
| Affiliation: | Division of Laboratories, Beth Israel Medical Center, New York, N.Y. 10003, U.S.A., and Department of Biochemistry, University College of Science, Calcutta University, Calcutta 19, India |
| |
| Abstract: | 1. The action of mescaline sulphate on the hydrogen-bonded structure of the RNA constituent of ribosomes of goat brain-cortex slices was studied by using the hyperchromic effect of heating and formaldehyde reaction. 2. The ribosomal total RNA species of the mescaline-treated brain-cortex slices have a smaller proportion of hydrogen-bonded structure than the ribosomal RNA species of the untreated brain-cortex slices. 3. Mescaline also appears to have affected this lowering of hydrogen-bonded structure of the ribosomal 28S RNA of brain-cortex tissue. |
| |
| Keywords: | |
|
|
