Enzymatic hydrolysis of asymmetric heterocyclic amino acid derivatives |
| |
Authors: | M. Pugnière F. Kraicsovits M-A. Coletti-Previero A. Previero |
| |
Affiliation: | (1) INSERM (58), 60 rue de Navacelles, 34100 Montpellier, France;(2) CNRS (ERA 555), 34100 Montepplier, France |
| |
Abstract: | Summary 2-methyl-oxazolinones and thio-thiazolidones representative of aromatic and aliphatic amino acids were hydrolysed by -chymotrypsin and subtilisin. The parametric ratio kcat/Km, correlated with the enantiomeric enrichment of the reaction product, indicates that thio-thiazolidones are converted to free amino acids by enzyme with the higher degree of stereospecificity. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|