Transcriptional regulation of subclass 5b fimbriae |
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Authors: | Maria D Bodero Elizabeth A Harden George P Munson |
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Affiliation: | (1) Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL PO Box 016960 (R138), 33101, USA |
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Abstract: | Background Enterotoxigenic Escherichia coli (ETEC) is a major cause of infant and child mortality in developing countries. This enteric pathogen causes profuse watery diarrhea by elaborating one or more enterotoxins that intoxicate eukaryotic cells and ultimately leads to a loss of water to the intestinal lumen. Virulence is also dependent upon fimbrial adhesins that facilitate colonization of the small intestine. |
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