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Spatial constraints within the chlamydial host cell inclusion predict interrupted development and persistence
Authors:Alexander Hoare  Peter Timms  Patrik M Bavoil  David P Wilson
Institution:(1) National Centre in HIV Epidemiology and Clinical Research, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia;(2) Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, QLD, Australia;(3) Department of Biomedical Sciences, University of Maryland Baltimore, MD, USA
Abstract:

Background  

The chlamydial developmental cycle involves the alternation between the metabolically inert elementary body (EB) and the replicating reticulate body (RB). The triggers that mediate the interchange between these particle types are unknown and yet this is crucial for understanding basic Chlamydia biology.
Keywords:
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