Electron transport chains in organohalide-respiring bacteria and bioremediation implications |
| |
Authors: | Shanquan Wang Lan Qiu Xiaowei Liu Guofang Xu Michael Siegert Qihong Lu Philippe Juneau Ling Yu Dawei Liang Zhili He Rongliang Qiu |
| |
Institution: | 1. School of Environmental Science and Engineering, Sun Yat-Sen University, Guangzhou 510275, China;2. Environmental Microbiome Research Center, Sun Yat-Sen University, Guangzhou 510275, China;3. Guangdong Provincial Key Laboratory of Environmental Pollution Control and Remediation Technology, Guangzhou 510275, China;4. College of Biotechnology, Tianjin University of Science & Technology, Tianjin 300457, China;5. Department of Biological Sciences, University of Quebec in Montreal, Montreal, Canada;6. Beijing Key Laboratory of Bio-inspired Energy Materials and Devices, School of Chemistry and Environment, Beihang University, Beijing 100191, China |
| |
Abstract: | In situ remediation employing organohalide-respiring bacteria represents a promising solution for cleanup of persistent organohalide pollutants. The organohalide-respiring bacteria conserve energy by utilizing H2 or organic compounds as electron donors and organohalides as electron acceptors. Reductive dehalogenase (RDase), a terminal reductase of the electron transport chain in organohalide-respiring bacteria, is the key enzyme that catalyzes halogen removal. Accumulating experimental evidence thus far suggests that there are distinct models for respiratory electron transfer in organohalide-respirers of different lineages, e.g., Dehalococcoides, Dehalobacter, Desulfitobacterium and Sulfurospirillum. In this review, to connect the knowledge in organohalide-respiratory electron transport chains to bioremediation applications, we first comprehensively review molecular components and their organization, together with energetics of the organohalide-respiratory electron transport chains, as well as recent elucidation of intramolecular electron shuttling and halogen elimination mechanisms of RDases. We then highlight the implications of organohalide-respiratory electron transport chains in stimulated bioremediation. In addition, major challenges and further developments toward understanding the organohalide-respiratory electron transport chains and their bioremediation applications are identified and discussed. |
| |
Keywords: | Electron transport chain Organohalide-respiring bacteria Microbial reductive dehalogenation Bioremediation |
本文献已被 ScienceDirect 等数据库收录! |
|