Fatty liver induction: inverse relationship between hepatic neutral lipid accumulation and dietary polyunsaturated fatty acids in orotic acid-fed rats |
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Authors: | L A Witting |
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Abstract: | The levels of hepatic neutral lipids in the orotic acid-fed rat were inversely related to the dietary levels of polyunsaturated fatty acids, as in the choline-deficient rat. Hepatic microsomal protein and phospholipid and total hepatic phospholipid were increased in orotic acid-induced fatty livers. The increase in phospholipid was largely restricted to the phosphatidylethanolamines. |
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