Management of twin-twin transfusion syndrome: laying the foundation for future interventional studies.

Twin-twin transfusion syndrome is the most common complication of monochorionic pregnancies affecting between 5 and 15% of such pregnancies and accounts for 15-77% of perinatal mortality in twins. The management of twin-twin transfusion syndrome is complex and various treatment modalities have been tried. This review critically evaluates the different management options available for the syndrome and recommends some guidelines for future interventional studies.