Molecular cloning and characterization of a mouse alpha 2C2 adrenoceptor subtype gene. |
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| Authors: | W M Chen A C Chang B J Shie Y H Chang N C Chang |
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| Affiliation: | Institute of Microbiology and Immunology, Neuroscience and Clinical Medicine, National Yang-Ming Medical College, Taipei, Taiwan, ROC. |
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| Abstract: | A clone MA2C2 encoding the murine homologue of adrenoceptor alpha 2C2 was isolated from a mouse genomic library using a subtype specific probe. The nucleotide and the deduced amino acid sequences derived from an ApaI fragment (2 kb) of the clone reveal a single open reading frame encoding a putative receptor protein of 455 amino acids. The 5' untranslated region (0.5 kb) sequenced is characterized by high GC content and CpG island count. |
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