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Electron Cryo-microscopy Structure of Ebola Virus Nucleoprotein Reveals a Mechanism for Nucleocapsid-like Assembly
Authors:Zhaoming Su  Chao Wu  Liuqing Shi  Priya Luthra  Grigore D. Pintilie  Britney Johnson  Justin R. Porter  Peng Ge  Muyuan Chen  Gai Liu  Thomas E. Frederick  Jennifer M. Binning  Gregory R. Bowman  Z. Hong Zhou  Christopher F. Basler  Michael L. Gross  Daisy W. Leung  Wah Chiu  Gaya K. Amarasinghe
Affiliation:1. Department of Bioengineering and Department of Microbiology and Immunology, James H. Clark Center, Stanford University, Stanford, CA 94305, USA;2. Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA;3. Department of Chemistry, Washington University in St. Louis, St. Louis, MO 63130, USA;4. Center for Microbial Pathogenesis, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303, USA;5. Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA;6. Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110, USA;7. Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles (UCLA), Los Angeles, CA 90095, USA
Abstract:
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  • Keywords:Ebola virus  cryo-EM  nucleocapsid  nucleoprotein  viral RNA synthesis
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