Protein phosphatase activities in vivo in Xenopus laevis oocyte: inhibition by okadaic acid |
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| Authors: | P Cormier O Mulner-Lorillon R Ozon R Bellé |
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| Institution: | Laboratoire de Physiologie de la Reproduction, UA CNRS 555, INRA, UPMC, Paris, France. |
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| Abstract: | Protein phosphatase activities were analyzed in vivo in Xenopus oocytes. The dephosphorylation of microinjected beta casein was inhibited when the tumor promoter okadaic acid was microinjected into oocytes. Inhibition was dose dependent and reversible; 50% of activity was recovered 15-30 minutes after microinjection. |
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| Keywords: | Protein phosphatase in vivo okadaic acid- Xenopus oocyte-protein phosphatase 2A |
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