Phosphoinositides in the developing inner ear with references to brain, kidney and liver of the mouse |
| |
| Authors: | M Anniko J Schacht |
| |
| Affiliation: | 1. Department of Otolaryngology, Karolinska Hospital, S-104 01 Stockholm, Sweden;2. King Gustaf V Research Institute. Karolinska Institutet. S-104 01 Stockholm, Sweden;1. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas (INIFTA, UNLP, CCT La Plata-CONICET), Diagonal. 113 y 64, Sucursal 4, Casilla de correo 16, (B1900ZAA) La Plata, Argentina;2. Laboratoire des Interactions Moléculaires et Réactivité Chimique et Photochimique (IMRCP), UMR CNRS 5623, Université Toulouse III (Paul Sabatier UPS), 118, route de Narbonne, Toulouse cédex 9 F-31062 France;3. Instituto da Investigaciones en Biodiversidad y Medio Ambiente (INIBIOMA, CONICET), Centro Regional Universitario Bariloche, Universidad Nacional del Comahue Quintral 1250 (8400) Argentina;1. INESC Coimbra, DEEC, Rua Sílvio Lima, Pólo II, Coimbra 3030-290, Portugal;2. Department of Electrical and Computer Engineering, University of Coimbra, Rua Sílvio Lima, Pólo II, Coimbra 3030-290, Portugal;3. CeBER and Faculty of Economics, University of Coimbra, Av. Dias da Silva 165, Coimbra 3004-512, Portugal;1. Department of Pediatrics and Institute of Molecular Medicine, College of Medicine, National Cheng-Kung University, Tainan, Taiwan;2. Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan;3. Division of Research Development, Vita Genomics Inc., Taipei, Taiwan;4. Institute of Medical Sciences, Tzu Chi University, Hualien, Taiwan;1. New Technologies – Research Centre, University of West Bohemia, Univerzitni 8, 306 14 Pilsen, Czech Republic;2. Center of Excellence Geopolymer and Green Technology, School of Material Engineering, University Malaysia Perlis, 01007 Kangar, Perlis, Malaysia;3. Council of Scientific and Industrial Research – National Physical Laboratory Dr. K S Krishnan Marg, New Delhi 110012, India |
| |
| Abstract: | - 1.1. Polyphosphoinositide turnover is high in adult nervous or secretory tissues.
- 2.2. In the developing inner ear of the mouse, incorporation of 32P1 into these lipids is rapid while that of [3H]inositol proceeds phosphatidylinositol s⪢ polyphosphoinositides.
- 3.3. In chase experiments, 32P-label is lost from the latter but not from other lipids.
- 4.4. Fetal brain, liver and kidney show similar 32P-labeling patterns.
- 5.5. Thus, rapid turnover of polyphosphoinositides can already be demonstrated in functionally immature tissues.
|
| |
| Keywords: | |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ |
|
