细胞因子对创伤愈合的影响

创伤愈合是一个复杂的生物学过程，涉及炎症细胞，修复细胞、细胞外基质以及细胞因子之间的相互作用。传统将这一过程分为炎症期、增值期、组织重构三个相互重叠的时期。细胞因子是一类对细胞生长、分化有明显调控作用的小分子生物活性多肽。是细胞与细胞外基质间重要的信号传导物。多种生长因子被释放到伤口部位被认为是创伤愈合所必需的。本文就细胞因子对创伤愈合的促进作用、细胞因子相互之间的协同作用，以及应用前景作以概述。

Effect of Cytokines on the Process of Wound Healing

Wound healing is a complex biological process that requires cellular interactions between a variety of inflammatory cells, wound repair cells, extracellular matrices （ECMs） and Cytokines. Wound healing is a process involving inflammation, new tissue formation, and finally tissue remodeling. Cytokines are a class of small molecule peptide which have significant regulatory functions in cell growth and differentiation. They are important signal transmitters between cell and the extraeellular matrix. Several Cytokines that are released at the wound site are presumed to be necessary for wound healing. This review summarized Cytokines effect on the process of wound healing, the interactions between different Cytokines, and finally we discussed the perspective of them.