Occurrence of aminopropylcadaverine and its aminopropyl derivatives aminopentylnorspermidine and N, N' -bis(3-aminopropyl)cadaverine in Halococcus acetoinfaciens |
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| Authors: | Koei Hamana Masaru Niitsu Keijiro Samejima Shigeru Matsuzaki |
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| Institution: | Colloge of Medical Care and Technology, Gunma University, Maebashi, Japan;Department of Pharmaceutical Chemistry, Josai University, Saitama, Japan;Department of Physiology, Institute of Endocrinology, Gunma University, Maebashi, Japan |
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| Abstract: | Abstract Besides putrescine, cadaverine, spermidine, spermine and thermospermine, three novel polyamines were detected in a slightly halophilic eubacterium Halococcus acetoinfaciens (IAM 12094, ATCC 25861). These novel polyamines were found to be N -3-aminopropylcadaverine NH2(CH2)3NH(CH2)5NH2] and its aminopropyl derivatives: aminopentylnorspermidine NH2(CH2)3NH(CH2)3NH(CH2)5NH2] and N , N ' -bis(3-aminoprophyl)cadaverine NH2(CH2)3 NH(CH2)5NH(CH2)3NH2]. Aminopropylcadaverine was also detected in two other species, Halococcus agglomeratus (IAM 12095, ATCC 25862) and Halococcus nondenitrificans (IAM 12096, ATCC 25863). |
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| Keywords: | Aminopropylcadaverine Aminopentylnorspermidine N N'-Bis(3-aminopropyl)cadaverine Polyamine Halococcus |
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