Serum biochemical values in two inbred strains of mastomys (Praomys coucha). |
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| Authors: | Y Yamamoto Y Noguchi A Noguchi K Nakayama K Mochida K Takano M Koura A Ogura |
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| Institution: | Department of Veterinary Science, National Institute of Infectious Diseases, Tokyo, Japan. |
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| Abstract: | Serum samples collected from 119 (72 male and 47 female) mastomys (Praomys coucha) of 2 specific-pathogen-free inbred strains (RI4 and RI7) were analyzed for 12 serum biochemical parameters. Sex-related differences (p < 0.01) were noted in alkaline phosphatase and glucose; the both higher in females than in males. Age-related changes (p < 0.01) were observed in total protein, albumin, total cholesterol, and alkaline phosphatase, with higher values for the first three parameters in the older group (200-250 days of age) than in the younger group (90-140 days of age). Four out of 12 parameters showed strain-related differences (p < 0.01), consistent with the large amount of genetic heterogeneity reported in this species. These serum biochemical reference values should provide information for the use of mastomys in laboratory research. |
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