A Monte Carlo software bench for simulation of spectral k-edge CT imaging: Initial results |
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| Affiliation: | 1. Department of Diagnostic and Interventional Radiology, Technische Universität München, Munich, Germany;2. Institute of Medical Physics and Radiation Protection, University of Applied Sciences, Giessen, Germany;1. University of Tübingen, Department of Diagnostic and Interventional Radiology, Eberhard-Karls-University, Hoppe-Seyler-Str.3, 72076 Tübingen, Germany;2. Technische Universität München, M2—Lehrstuhl für Numerische Mathematik, Boltzmannstraße 3, 85748 Garching, Germany;3. Technische Universität München, M6—Lehrstuhl für Mathematische Modellierung, Boltzmannstraße 3, 85748 Garching, Germany;1. Wuhan National Laboratory for Optoelectronics, Wuhan, Hubei 430074, China;2. Biomedical Engineering Department, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China;3. The Department of Radiology, The University of Chicago, Chicago, IL 60637, USA;1. Erlangen, Deutschland;2. Kiel, Deutschland;1. Department of Radiology, University Medical Center Utrecht, P.O. Box 85500, E01.132, Utrecht 3508 GA, The Netherlands;2. Department of Radiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands;3. Department of Radiology, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands;4. Department of Radiology, Maastricht University Medical Center, Maastricht, The Netherlands;5. Center for Medical Imaging North East Netherlands, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands |
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| Abstract: | PurposeSpectral Computed Tomography (SCT) systems equipped with photon counting detectors (PCD) are clinically desired, since such systems provide not only additional diagnostic information but also radiation dose reductions by a factor of two or more. The current unavailability of clinical PCDs makes a simulation of such systems necessary.MethodsIn this paper, we present a Monte Carlo-based simulation of a SCT equipped with a PCD. The aim of this development is to facilitate research on potential clinical applications. Our MC simulator takes into account scattering interactions within the scanned object and has the ability to simulate scans with and without scatter and a wide variety of imaging parameters. To demonstrate the usefulness of such a MC simulator for development of SCT applications, a phantom with contrast targets covering a wide range of clinically significant iodine concentrations is simulated. With those simulations the impact of scatter and exposure on image quality and material decomposition results is investigated.ResultsOur results illustrate that scatter radiation plays a significant role in visual as well as quantitative results. Scatter radiation can reduce the accuracy of contrast agent concentration by up to 15%.ConclusionsWe present a reliable and robust software bench for simulation of SCTs equipped with PCDs. |
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| Keywords: | Monte Carlo simulation Spectral CT Photon-counting detectors Material decomposition |
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