Malnutrition and cachexia in patients with head and neck cancer treated with (chemo)radiotherapy |
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Authors: | Mojca Gorenc Nada Rotovnik Kozjek Primo? Strojan |
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Institution: | 1. Department of Radiation Oncology, Institute of Oncology Ljubljana, Zalo?ka 2, SI-1000 Ljubljana, Slovenia;2. Clinical Nutrition Unit, Institute of Oncology Ljubljana, Zalo?ka 2, SI-1000 Ljubljana, Slovenia |
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Abstract: | AimTo highlight the problems associated with nutrition that occur in patients with squamous cell carcinoma of the head and neck (SCCHN).BackgroundSCCHN is associated with weight loss before, during and after radiotherapy or concurrent chemoradiotherapy. Because of serious consequences of malnutrition and cachexia on treatment outcome, mortality, morbidity, and quality of life, it is important to identify SCCHN patients with increased risk for the development of malnutrition and cachexia.Materials and methodsCritical review of the literature.ResultsThis review describes pathogenesis, diagnosis and treatment of malnutrition and cancer cachexia. Treatment of malnutrition and cancer cachexia includes nutritional interventions and pharmacological therapy. Advantages and disadvantages of different nutritional interventions and their effect on the nutritional status, quality of life and specific oncological treatment are presented.ConclusionsNutritional management is an essential part of care of these patients, including early screening, assessment of nutritional status and appropriate intervention. |
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Keywords: | Weight loss Malnutrition Cachexia Head and neck cancer Radiotherapy |
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