A practical tool to evaluate dose distributions using radiochromic film in radiation oncology |
| |
| Institution: | 1. Maternal and Child Health Research Program, Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA;2. Department of Biostatics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA;3. Department of Biological and Physiological Sciences, Universidad Peruana Cayetano Heredia, Lima, Peru;4. Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru;1. The Pediatric Neurology and Developmental Unit, Loewenstein Rehabilitation Hospital, Raanana, Israel;2. Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel;3. Epilepsy Service, Schneider Children''s Medical Center, Petach Tikva, Israel;4. Pediatric Neurology Unit, Schneider Children''s Medical Center, Petach Tikva, Israel;5. Department of Rehabilitation, Sheba Medical Center, Ramat Gan, Israel;6. Department of Child Neurology and Rehabilitation, Assaf Harofeh Medical Center, Zerifin, Israel;7. Child Development Center, Schneider Children''s Medical Center, Petach Tikva, Israel;8. Soroka Medical Center, Beer-Sheva, Israel;9. Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel;10. Pediatric Cardiology Unit, Schneider Children''s Medical Center, Petach Tikva, Israel;11. Pediatric Neurology Unit, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel |
| |
| Abstract: | PurposeTriple channel algorithm and specific procedures make more reliable radiochromic dosimetry for treatment planning verification and quality assurance in radiation therapy. A tool to obtain radiochromic dose distributions and compare them with the ones resulting from a treatment planning system was developed and applied.MethodsThe tool was developed as Microsoft Excel macro; it builds dose calibration curves against net optical density of Gafchromic EBT3 film, produces axial, coronal and sagittal dose maps and allows to evaluate them against dose distributions calculated by the Varian treatment planning system Eclipse using gamma index and gamma angle.ResultsThe net optical density standard errors of estimate of calibration curves at 6 MV Varian DBX600 linac energy were 0.2%, 0.4% and 0.2% for the red, green and blue channels. Tests of these curves by means of three independent eight dose points measurement series, at 15 MV and 6 MV Varian 2100C linac and at 6 MV DBX600 linac energies, showed less than 2% of dose errors for the red channel and less than 3% for the green channel in the range 100–450 cGy. The comparisons between dose distributions from Gafchromic EBT3 triple channel algorithm and the ones from Eclipse analytic anisotropic algorithm (AAA) showed values of gamma index 95th percentile between 0.6 and 1.0.ConclusionThe obtained results encourage the application of this tool in radiation therapy quality assurance. |
| |
| Keywords: | Radiochromic dosimetry Treatment planning verification Gamma index analysis Quality assurance |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
