Effect of prior vaccination on experimental Blastomycosis |
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| Authors: | Marshall E Landay Masao Hotchi Nirmolini Soares |
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| Institution: | (1) Clinical Laboratories The Jewish Hospital Cincinnati, 45229, Ohio |
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| Abstract: | Immunogens were found associated with particular fractions prepared from spherules ofCoccidioides immitis (Kong, Levine &Smith, 1963) and from yeast cells ofHistoplasma capsulatum (Salvin &Ribi, 1955). However,Blastomyces dermatitidis, another dimorphic systemic fungal pathogen was shown to elicit a minimal immunogenic response in experimental animals (Kong &Levine, 1967). It was therefore deemed pertinent to study factors which might enhance the resistance of mice to infection withB. dermatitidis. |
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