The carboxy-terminal sequence of p56lck can regulate p60c-src. |
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| Authors: | A MacAuley and J A Cooper |
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| Institution: | Department of Cell Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington 98104. |
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| Abstract: | A chimera containing the coding region for residues 1 to 516 of p60c-src and residues 495 to 509 (the carboxy terminus) of p56lck was constructed and expressed in mouse fibroblasts. The chimeric protein appeared to be phosphorylated and regulated in the same fashion as p60c-src. |
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