Immunochemical Characterization of Plaque Mutants of Simian Virus 40 |
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Authors: | H L Ozer K K Takemoto R L Kirschstein and D Axelrod |
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Institution: | Laboratory of Viral Diseases and Laboratory of Biology of Viruses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20014 |
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Abstract: | Analysis of large and small plaque mutants of simian virus 40 using antisera prepared against each has revealed quantitative and possibly qualitative antigenic differences for each plaque type. A sensitive micro radioisotope precipitation test permitted evaluation of immunochemical similarities and differences of capsid antigens by inhibition of precipitation. |
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