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Enhancement of carnitine acetyltransferase synthesis in alkane-grown cells and propionate-grown cells of Candida tropicalis
Authors:Mitsuyoshi Ueda  Atsuo Tanaka  Saburo Fukui
Affiliation:(1) Laboratory of Industrial Biochemistry, Department of Industrial Chemistry, Faculty of Engineering, Kyoto University, Yoshida, Sakyo-ku, 606 Kyoto, Japan
Abstract:The level of carnitine acetyltransferase was markedly increased in harmony with appearance of peroxisomes in alkane-grown cells and propionate-grown cells of Candida tropicalis. From immunochemical studies with antibodies against peroxisomal and mitochondrial carnitine acetyltransferases, it was confirmed that no other type of the enzyme than the peroxisomal and mitochondrial ones was present in alkane-, propionate- and glucose-grown cells of the yeast. The increase in the enzyme level in alkane- and propionate-grown cells was immunochemically proved to result from the increase in the amount of the enzyme protein.Dedicated to Professor Hans G. Schlegel on occasion of his 60th birthday
Keywords:Candida tropicalis  n-Alkanes  Propionate  Carnitine acethyltransferase  Peroxisomes  Enzyme induction  Immunochemical studies
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