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IL-10 Signaling Remodels Adipose Chromatin Architecture to Limit Thermogenesis and Energy Expenditure
Authors:Prashant Rajbhandari  Brandon J. Thomas  An-Chieh Feng  Cynthia Hong  Jiexin Wang  Laurent Vergnes  Tamer Sallam  Bo Wang  Jaspreet Sandhu  Marcus M. Seldin  Aldons J. Lusis  Loren G. Fong  Melanie Katz  Richard Lee  Stephen G. Young  Karen Reue  Stephen T. Smale  Peter Tontonoz
Affiliation:1. Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA;2. Molecular Biology Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA;3. Howard Hughes Medical Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA;4. Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA;5. Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA;6. Department of Medicine, Division of Cardiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA;7. Ionis Pharmaceuticals, Carlsbad, CA 92008, USA
Abstract:
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  • Keywords:adipogenesis  thermogenesis  immunometabolism  IL-10
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