Viral interactions with receptors in cell junctions and effects on junctional stability |
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Authors: | Spear Patricia G |
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Institution: | Department of Microbiology-Immunology, The Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. |
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Abstract: | Several viruses can use, as entry receptors, cell adhesion molecules that localize to junctional complexes of epithelial cells and other cell types. A recent publication in Cell describes how adenovirus can disrupt cell junctions, thereby effecting its release from basal surfaces of an infected epithelium to the apical or external environment. |
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