Prostaglandin-sepharose: Application to the purification of bovine lung 15 (S) -hydroxyprostaglandin dehydrogenase |
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Authors: | Michitaro Nagasawa James Amigo Chan Charles J. Sih |
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Affiliation: | School of Pharmacy, University of Wisconsin Madison, Wisconsin 53706 USA |
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Abstract: | Prostaglandins E1, F1α and A2 were covalently joined to the surface of Sepharose as carboxamide linkages. The insolubilized prostaglandins were shown to function effectively in the purification of 15(S) -hydroxyprostaglandin dehydrogenase. |
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