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Prostaglandin-sepharose: Application to the purification of bovine lung 15 (S) -hydroxyprostaglandin dehydrogenase
Authors:Michitaro Nagasawa   James Amigo Chan  Charles J. Sih
Affiliation:School of Pharmacy, University of Wisconsin Madison, Wisconsin 53706 USA
Abstract:Prostaglandins E1, F and A2 were covalently joined to the surface of Sepharose as carboxamide linkages. The insolubilized prostaglandins were shown to function effectively in the purification of 15(S) -hydroxyprostaglandin dehydrogenase.
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