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Discovery of O-Linked Carbohydrate on HIV-1 Envelope and Its Role in Shielding against One Category of Broadly Neutralizing Antibodies
Affiliation:1. Medical Scientist Training Program, Miller School of Medicine, University of Miami, Miami, FL, USA;2. Department of Pathology, Miller School of Medicine, University of Miami, Miami, FL, USA;3. Department of Life Sciences, Imperial College London, London, UK;4. Infectious Diseases Section, Miami Veterans Affairs Health Care System, University of Miami, Miami, FL, USA;5. Department of Medicine, Miller School of Medicine, University of Miami, Miami, FL, USA;6. Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, USA
Abstract:
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  • Keywords:HIV-1  Envelope  gp120  V1 domain  O-glycosylation  broadly neutralizing antibodies  immune evasion  escape mechanism
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