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Cyclopentenone Prostaglandins and Structurally Related Oxidized Lipid Species Instigate and Share Distinct Pro- and Anti-inflammatory Pathways
Institution:1. Institute of Molecular Health Sciences, ETH Zürich, 8093 Zürich, Switzerland;2. Laboratory of Organic Chemistry, ETH Zürich, 8093 Zürich, Switzerland;3. Department of Biochemistry, University of Lausanne, 1066 Epalinges, Switzerland
Abstract:
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  • Keywords:oxidized phospholipids  15d-PGJ2  cyclopentenone prostaglandins  Nrf2  caspase-8  inflammatory apoptosis  OXPHOS  IL-1β  dendritic cells  macrophages
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