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Defining Epidermal Basal Cell States during Skin Homeostasis and Wound Healing Using Single-Cell Transcriptomics
Affiliation:1. Department of Biological Chemistry, School of Medicine, University of California, Irvine, CA 92697, USA;2. The NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, CA 92627, USA;3. Department of Mathematics, University of California, Irvine, CA 92697, USA;4. Laboratory for Fluorescence Dynamics, Department of Biomedical Engineering, University of California, Irvine, CA 92697, USA;5. Center for Complex Biological Systems, University of California, Irvine, CA 92697, USA;6. Department of Developmental and Cell Biology, University of California, Irvine, CA 92697, USA
Abstract:
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  • Keywords:single-cell RNA sequencing  skin  stem cell  epidermis  wound healing  metabolism  basal cell state  cellular transition dynamics  FLIM  plasticity
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