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Chronic Peripheral Inflammation Causes a Region-Specific Myeloid Response in the Central Nervous System
Institution:1. Department of Molecular Neurology, Friedrich Alexander University Erlangen-Nürnberg, University Hospital Erlangen, 91054 Erlangen, Germany;2. Institute of Neuropathology, Faculty of Medicine, University of Freiburg, 79106 Freiburg im Breisgau, Germany;3. Department of Internal Medicine 3, Friedrich Alexander University Erlangen-Nürnberg, University Hospital Erlangen, 91054 Erlangen, Germany;4. Deutsches Zentrum für Immuntherapie, 91054 Erlangen, Germany;5. Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA;6. Signalling Research Centres for BIOSS and CIBSS, University of Freiburg, 79104 Freiburg im Breisgau, Germany;7. Center for Basics in NeuroModulation (NeuroModulBasics), Faculty of Medicine, University of Freiburg, 79104 Freiburg im Breisgau, Germany
Abstract:
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  • Keywords:chronic peripheral inflammation  CNS myeloid cells  brain regions  human rheumatoid arthritis  blood-brain barrier  microglia
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