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Neurokinin-1 Receptor Signaling Is Required for Efficient Ca2+ Flux in T-Cell-Receptor-Activated T Cells
Institution:1. Thomas E. Starzl Transplantation Institute, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA;2. Department of Surgery, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA;3. Department of Immunology, University of Pittsburgh, School of Medicine Pittsburgh, PA, USA;4. Department of Dermatology, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA;5. Flinders University, College of Medicine and Public Health, Adelaide, SA, Australia;6. Hubei Key Laboratory of Medical Technology on Transplantation, Transplant Center, Institute of Hepatobiliary Diseases, Zhongnan Hospital, Wuhan University, Wuhan, Hubei, China;7. Department of Cell Biology and Center for Biological Imaging, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA;8. The McGowan Center for Regenerative Medicine, Pittsburgh, PA, USA;9. Ontario Cancer Institute, Princess Margaret Hospital, Toronto, ON, Canada;10. Department of Bioengineering, University of Pittsburgh Swanson School of Engineering, Pittsburgh, PA, USA;11. The University of Pittsburgh Clinical and Translational Science Institute, Pittsburgh, PA, USA;12. The UPMC Hillman Cancer Center, Pittsburgh, PA, USA
Abstract:
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  • Keywords:neurokinin-1 receptor  T cell receptor  G-protein-coupled receptors  substance P  hemokinin-1  T cell activation  T cell bias  T cell survival
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