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Chronic Viral Infection Promotes Efficient Germinal Center B Cell Responses
Institution:1. Department of Biomedicine, Division of Experimental Virology, University of Basel, Haus Petersplatz, 4009 Basel, Switzerland;2. Development of the Immune System, Institut Necker-Enfants Malades, Institut National de la Santé et de la Recherche Médicale, U1151-Centre National de la Recherche Scientifique, UMR 8253, Faculté de Médecine Paris Descartes, Université Paris Descartes, Sorbonne Paris Cité, Paris, France;3. Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China;4. Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland;5. Department of Immunology, University of Oslo, Oslo, Norway;6. Department of Pathology and Immunology, Division of Clinical Pathology, University & University Hospital of Geneva, Geneva, Switzerland
Abstract:
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  • Keywords:chronic viral infection  germinal center B cells  neutralizing antibody  affinity maturation  lymphocytic choriomeningitis virus  LCMV  AID  memory B cell  antibody-secreting cell
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