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Small Molecule Inhibition of GSK-3 Specifically Inhibits the Transcription of Inhibitory Co-receptor LAG-3 for Enhanced Anti-tumor Immunity |
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| Affiliation: | 1. Cell Signalling Section, Department of Pathology, Tennis Court Road, University of Cambridge, Cambridge CB2 1QP, UK;2. Division of Immunology-Oncology Research Center, Maisonneuve-Rosemont Hospital, Montreal, QC H1T 2M4, Canada;3. Département de Medicine, Université de Montréal, Montreal, QC H3C 3J7, Canada;4. Leeds Institute of Medical Research, University of Leeds, School of Medicine, Wellcome Trust Brenner Building, St James’s University Hospital, Leeds LS9 7TF, UK |
| Abstract: |  |
| Keywords: | LAG-3 T cells immunotherapy PD-1 immune checkpoint GSK-3 small molecule inhibitors |
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