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The Amount of BCL6 in B Cells Shortly after Antigen Engagement Determines Their Representation in Subsequent Germinal Centers
Institution:1. Department of Immunology & Pathology, Alfred Medical Research and Education Precinct, Monash University, Level 6, Burnet Tower, 89 Commercial Road, Melbourne, VIC 3004, Australia;2. Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Solnavägen 9, 17165 Solna, Sweden;3. The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC 3052, Australia;4. Department of Medical Biology, The University of Melbourne, Parkville, VIC 3010, Australia
Abstract:
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  • Keywords:B cells  antibodies  BCL6  germinal centers  adaptive immunity  immune response  B cell memory  humoral immunity  clonal expansion  Bcl6 transgene  pre-germinal center
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