Neurotensin analogs indications for use as potential antipsychotic compounds |
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Authors: | McMahon Beth M Boules Mona Warrington Lewis Richelson Elliott |
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Affiliation: | Laboratory of Neuropharmacology, Mayo Foundation for Medical and Educational Research, Jacksonville, FL 32224, USA. McMahon.beth@mayo.edu |
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Abstract: | This review will be an update, focusing on the central nervous system (CNS) roles of the neurotransmitter, neurotensin. We will provide a summary of current knowledge about neurotensin, why it is an important peptide to study, and where the field is heading. Special emphasis is placed on the development of neurotensin analogs, which has been a major effort of our group, the potential role of neurotensin in Parkinson's disease, and the interaction of neurotensin with other neurotransmitters as evidenced by microdialysis studies. |
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Keywords: | Neurotensin Antipsychotic Neurotensin analogs Central nervous system |
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