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Review of the adipose derived stem cell secretome |
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| Authors: | Sahil K. Kapur Adam J. Katz |
| Affiliation: | 1. Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Wisconsin, Madison, G5/361 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792, USA;2. Laboratory of BioInnovation and Translational Therapeutics, Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Florida College of Medicine, 1600 SW Archer Road, P.O. Box 100138, Gainesville, FL 32610-0138, USA |
| Abstract: | Recent advances in protein detection and analysis have lead to multiple in depth studies that analyze the adipose-derived stem cell (ASC) secretome. These studies differ significantly in their methods of secretome preparation and analysis. Most of them use a pro-differentiation or pro-inflammatory stimulus to observe differential expression of secreted proteins. In spite of the variance in methodologies used, 68 proteins are reported to be commonly expressed in a majority of the studies and may serve as potential candidates for conserved secretome proteins. |
| Keywords: | Adipose-derived stem cell (ASC) Secretome Adipose tissue Stromal-vascular fraction Adipogenesis Niche |
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