Photochemical generation and reactions of heme cation radicals in heme proteins |
| |
| Authors: | E Magner G McLendon |
| |
| Institution: | Department of Chemistry, University of Rochester, NY 14627. |
| |
| Abstract: | A novel approach is described for generating reactive oxidizing centers in heme proteins, with zinc hemoglobin (Zn Hb) and zinc cytochrome c (Zn cyt c) used as examples. The reaction of 3Zn* Hb with CoIII(NH3)5 Cl]2+, and of 3Zn* cyt c with methyl viologen are described. In the case of Zn Hb the cation radical produced decays with a rate constant of k3 = 2400s-1. Using this value the rate of the reaction (formula; see text) can be calculated to be 4500s-1. |
| |
| Keywords: | |
|
|
