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Behavioural and physiological effects of methadone in the perioperative period on the Nile tilapia Oreochromis niloticus
Authors:Roberta M. Crivelaro  Roberto Thiesen  Marcela Aldrovani  Paloma E.S. Silva  Alexandre A.F. Barros Sobrinho  Paola C. Moraes
Affiliation:1. Department of Small Animal Medicine and Surgery, College of Agrarian and Veterinarian Sciences, Via de acesso, professor Paulo Donato Castellani, São Paulo State University (Unesp), Jaboticabal, Brazil;2. Pampa Federal University (Unipampa), Uruguaiana, Brazil
Abstract:Through the analysis of behavioural changes, this study demonstrates that methadone has behavioural, but not analgesic, effects on Oreochromis niloticus. It provides information that suggests the drug has sedative abilities, as the recovery time was shorter in the fish receiving methadone. Future research, with different doses and stimuli, is required to provide more information about analgesia.
Keywords:analgesia  pain  teleost  video-surgery
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