首页 | 本学科首页   官方微博 | 高级检索  
   检索      


Probiotic characteristics and in vitro compatibility of a combination of Bifidobacterium breve M-16 V,Bifidobacterium longum subsp. infantis M-63 and Bifidobacterium longum subsp. longum BB536
Authors:Toscano  Marco  De Vecchi  Elena  Gabrieli  Arianna  Zuccotti  Gian Vincenzo  Drago  Lorenzo
Institution:1.Department of Biomedical Sciences for Health, University of Milan, Via Mangiagalli 31, Milan, Italy
;2.IRCCS Galeazzi Orthopaedic Institute, Via R. Galeazzi 4, Milan, Italy
;3.San Donato Foundation Group, IRCSS Galeazzi Orthopaedic Institute, Via R. Galeazzi 4, Milan, Italy
;4.Department of Biomedical and Clinical Sciences, Luigi Sacco Hospital, Via G.B. Sacco 74, Milan, Italy
;
Abstract:The consumption of probiotic-based products has risen greatly in recent decades. Due to their probiotic characteristics, microorganisms such as lactobacilli and bifidobacteria are in daily use in the production of food supplements. In the present study, three bifidobacterial strains (Bifidobacterium breve M-16 V, Bifidobacterium longum subsp. infantis M-63 and Bifidobacterium longum subsp. longum BB536) were tested for growth compatibility, resistance to antimicrobial agents, antibacterial activity against pathogens, resistance to gastric acidity, bile salt hydrolysis and adhesion to the human intestinal epithelial cell line HT29. All of these strains were resistant to gentamycin, but none showed in vitro growth incompatibility or the presence of known resistance determinants. B. breve M-16 V had the best probiotic characteristics and, indeed, was the only strain possessing antibacterial activity against Escherichia coli and Klebsiella pneumoniae. All strains were resistant to simulated gastric juice, while only B. longum subsp. longum BB536 and B. breve M-16 V showed a bile salt hydrolytic activity. Interestingly, a strong adhesion to HT29 cells was observed in all Bifidobacterium strains. In conclusion, B. breve M-16 V, B. longum subsp. longum BB536 and B. longum subsp. infantis M-63 showed several promising characteristics as probiotic strains.
Keywords:
本文献已被 SpringerLink 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号