The identification of an epoxy-hydroxy acid as a product from the incubation of arachidonic acid with washed blood platelets |
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Authors: | Irene C. Walker R.L. Jones N.H. Wilson |
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Affiliation: | Department of Pharmacology, University of Edinburgh, 1, George Square, Edinburgh EH8 9JZ Scotland |
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Abstract: | An epoxy-hydroxy compound, 10-hydroxy-11,12-epoxy-eicosa-5,8,14-trienoic acid, has been identified as a product on incubation of arachidonic acid with washed blood platelets from human, horse, cat, dog and rabbit. Gas chromatographic - mass spectrometric (GC-MS) evidence of structure is discussed. |
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