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Androgen receptor expression in the rat prostate is down-regulated by dietary phytoestrogens
Authors:Trent?D?Lund  author-information"  >  author-information__contact u-icon-before"  >  mailto:tlund@colostate.edu"   title="  tlund@colostate.edu"   itemprop="  email"   data-track="  click"   data-track-action="  Email author"   data-track-label="  "  >Email author,Daniel?J?Munson,Herman?Adlercreutz,Robert?J?Handa,Edwin?D?Lephart
Affiliation:1.Department of Biomedical Sciences,Colorado State University,Fort Collins,USA;2.Institute for Preventive Medicine, Nutrition, and Cancer Folkh?lsan Research Center, and Division of Clinical Chemistry, Biomedicum, University of Helsinki,Finland;3.The Neuroscience Center and Department of Physiology and Developmental Biology,Brigham Young University,Provo,USA
Abstract:

Background  

It is well established that the growth of the prostate gland is a hormone-dependent phenomenon involving both androgenic and estrogenic control. Proliferation of prostate cells is, at least in part, under control of estrogen receptor beta (ER-beta). Phytoestrogens bind ER-beta with high affinity and therefore may have antiproliferative effects in the prostate.
Keywords:
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