FunnyBase: a systems level functional annotation of Fundulus ESTs for the analysis of gene expression |
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| Authors: | Paschall Justin E Oleksiak Marjorie F VanWye Jeffrey D Roach Jennifer L Whitehead J Andrew Wyckoff Gerald J Kolell Kevin J Crawford Douglas L |
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| Affiliation: | (1) Division of Molecular Biology and Biochemistry, University of Missouri-Kansas City 64110, 5100 Rockhill Rd., USA;(2) Department of Environmental & Molecular Toxicology, North Carolina State University; Raleigh, 27695-7633, NC, USA;(3) Division of Marine Biology and Fisheries, NIEHS Marine and Freshwater Biomedical Sciences Center, Rosenstiel School of Marine & Atmospheric Science, University of Miami, 33149 Miami, FL, USA |
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| Abstract: | Background While studies of non-model organisms are critical for many research areas, such as evolution, development, and environmental biology, they present particular challenges for both experimental and computational genomic level research. Resources such as mass-produced microarrays and the computational tools linking these data to functional annotation at the system and pathway level are rarely available for non-model species. This type of "systems-level" analysis is critical to the understanding of patterns of gene expression that underlie biological processes. |
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