A probabilistic model for the evolution of RNA structure |
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Authors: | Email author" target="_blank">Ian?HolmesEmail author |
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Institution: | (1) Department of Bioengineering, University of California, Berkeley, CA 94720-1762, USA;(2) Department of Statistics, , 1 South Parks Road, Oxford, OX1 3TG, UK |
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Abstract: | Background For the purposes of finding and aligning noncoding RNA gene- and cis-regulatory elements in multiple-genome datasets, it is useful to be able to derive multi-sequence stochastic grammars (and
hence multiple alignment algorithms) systematically, starting from hypotheses about the various kinds of random mutation event
and their rates. |
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Keywords: | |
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